University of Minnesota
University Imaging Center
http://uic.umn.edu/
612.624.7938
University Imaging Centers - Where the University sees the future

Equipment

Equipment Description Location

Amersham Imager 600UV

The Amersham Imager 600UV is a sensitive and robust imager for chemifluorescence, UV transillumination, and UV fluorescence analysis of protein and DNA samples in gels and membranes.

Room 1-164 Jackson Hall
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Bruker Xtreme Optical and X-ray small animal imaging system

ATTENTION: THIS SYSTEM IS LOCATED IN THE CANCER CARDIOVASCULAR RESEARCH BUILDING, RM 1-250E. PLEASE CONTACT UIC STAFF FOR ACCESS AND TRAINING BEFORE USING.

The Xtreme system combines high-sensitivity optical molecular imaging (Biolumenescence and Fluorescence) along with high-resolution digital x-ray to deliver precise anatomical localization of molecular and cellular biomarkers in vivo.  Software automation simplifies complex multimodal imaging protocols for small animal imaging. The system includes animal handling features such as a heated sample shelf, a gas anesthesia system and MARS 360 degree animal rotation system (https://www.youtube.com/watch?v=V49qHYAqWsY). 

Bone denstiy measurements are possible: https://www.youtube.com/watch?v=FPfd6_5rung

System purchased with the generous support of the OVPR, CBS and AHC/Medical School through an I3 award. 

•Please do not use this equipment without contacting UIC staff for training and approval. Request training here:

  http://uic.umn.edu/node/add/training-request

•Please return all animals to the Catch Room (rm 1-370F) following imaging.  Contact RAR staff for housing information.

•Please contact UIC staff with any questions.

  http://uic.umn.edu/

 

Room 1-250E CCRB

CareStream Gel Pro 212 Imager

This versatile, easy-to-use system is ideal for imaging fluorescence or colorimetric data in sample formats such as gels (DNA/Coomassie/Silver stain) membranes, and 96 well plates. Carestream Molecular Imaging software (included) features a variety of new, easy-to-use functionalities such as true autofocus and directed autoexposure make it easy to capture perfectly exposed images in just a few clicks. The system is equipped with a thermal printer.

McGuire Translational Research Facility (Minneapolis Campus)

IVIS Spectrum In Vivo Imaging System

The IVIS Spectrum is the most versatile and advanced in vivo imaging system available on the market today. An optimized set of high efficiency filters and spectral un-mixing algorithms lets you take full advantage of bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. It also offers single-view 3D tomography for both fluorescent and bioluminescent reporters that can be analyzed in an anatomical context using our Digital Mouse Atlas.

For advanced fluorescence imaging, the IVIS Spectrum has the capability to use either trans-illumination (from the bottom) or epi-illumination (from the top) to illuminate in vivo fluorescent sources. 3D diffuse fluorescence tomography can be performed to determine source localization and concentration using the combination of structured light and trans illumination fluorescent images. The instrument is equipped with 10 narrow band excitation filters (30nm bandwidth) and 18 narrow band emission filters (20nm bandwidth) that assist in significantly reducing autofluorescence by the spectral scanning of filters and the use of spectral unmixing algorithms. In addition, the spectral unmixing tools allow the researcher to separate signals from multiple fluorescent reporters within the same animal.

Additional details, specifications and vendor protocols can be found here: http://www.perkinelmer.com/Catalog/Product/ID/IVISSPE

 

Room 1-166A Jackson Hall

Maestro In-Vivo Imaging System

Maestro provides users with a patented method of removing autofluorescence emitted from images of plant and animal tissues to reveal otherwise hard-to-detect labeled targets of interest. The dramatic improvement in signal-to-noise can increase sensitivity up to several hundred-fold, enabling much smaller or fainter signals from biological targets to be detected earlier and accurately measured. The increased sensitivity over standard imaging techniques provided by Maestro’s high-quality spectral imaging technology enable experiments and models which simply cannot be performed on any other system.

Room 37A Snyder Hall

Storm 860 Molecular Imager

The Storm 860 Molecular Imager Gel and Blot Imaging System offers filmless autoradiography, fluorescence and chemifluorescence imaging. Equipped with 450 nm  and 635 nm excitation lasers.

23 Snyder Hall (Saint Paul Campus)

Typhoon FLA 9500

Typhoon FLA 9500 is a variable mode laser scanner with modular access to the optical components, providing both versatile and flexible imaging for precise quantitation of proteins, nucleic acids, and other biomolecules.

1-151 Jackson Hall (Minneapolis Campus)