University of Minnesota
University Imaging Center
University Imaging Centers - Where the University sees the future


The University Imaging Centers are Hiring

The University Imaging Centers are Hiring!

We are seeking applicants who are service-oriented team players with excellent interpersonal, organizational and communication skills who enjoy moving science forward using state-of-the-art imaging resources.

The successful candidate will join a team of UIC associates responsible for the daily interactions of a dynamic interdisciplinary core facility at a major research University. This candidate will support and advance imaging projects primarily at our Jackson Hall location. This will include working on widefield, confocal, two photon, in vivo imaging and other efforts by the UIC.

We are looking for a degree in biology, chemistry or biomedical imaging. There is a need to be ready to help researchers with both trivial and advanced aspects of imaging projects. Experience in sample preparation (fixation, staining, antibody labeling, etc.), and advanced light microscopy is required and/or some experience with image analysis would be a strong plus. The successful candidate should be prepared to be in a dynamic multi-user environment whereby four basic areas of service must be covered:

  • Maximize the availability of advanced imaging technologies and methodologies to faculty, staff, students and external users. 
  • Bring expertise in new imaging technologies to users.
  • Educate the University community about new imaging technologies.
  • Promote interaction between developers of new imaging technology and potential users.

To learn more about the position or apply visit the UMN job posting.

3i Cleared Tissue LighSheet Microscope (CLTS)


The University Imaging Centers are excited to announce the installation of 3i's Cleared Tissue LightSheet microscope at the UIC Jackson Hall facility.

Cleared Tissue LightSheet (CTLS) is a large field light-sheet microscope designed to image whole organs at high speed. CTLS creates a focused sheet with a narrow waist for better optical sectioning, then uses a spatial light modulator (SLM) to rapidly shift the waist of the sheet along the axis of propagation. A dual excitation setup allows imaging from the right and left sides of the specimen for optimal light-sheet projection throughout. Piezoelectric stages move the specimen in x, y, and z with sub-micron resolution. The result is clear: a 1 cm3 volume can be imaged at up to 1µm x 1µm x 3µm (XYZ) resolution, and a cleared mouse brain can be imaged in as little as 1.5 hours.

Light sheet microscopy is a powerful technique for imaging large specimens by taking full advantage of emerging tissue clearing methods. The chemistry behind these techniques has advanced to where we can easily penetrate 1, 5 even 10mm into a specimen with a focused sheet of light. In combination with a macro zoom microscope using high NA large field of view lenses, Cleared Tissue LightSheet can image large field sizes with high resolution in short periods of timeCTLS acquisition is extremely flexible, from ultrafast capture with a 20μm light sheet to high-resolution capture with a 3μm light-sheet shifted 20 times and the resulting 20 sections of best focus tiled to one best-focus image.

Introduction to 3D Structured Illumination: From Widefield to Superresolution Imaging

The USDA Cereal Disease Lab at University of Minnesota is hosting a ZEISS workshop .

An overview of optical sectioning methods for improving the Z resolution for any major type of fluorescent microscope is presented, with a particular emphasis on concepts of structured illumination. Using illumination principles both old and new, these techniques allow for easy ways of creating confocal-like or superresolution-specifics 3D datasets. A Zeiss Axio Imager 2 fluorescent microscope with Apotome

2 will be available for demos and hands-on trials.


Thursday August 29 10:00 AM

Demo and Hands-on

Thursday August 29 11:00 AM - 3 PM


University of Minnesota - St. Paul Campus

USDA Cereal Disease Lab Room 107, 1551 Lindig Street, St. Paul, MN 55108

To register, request a demonstration, or ask additional questions, please contact:

Kimberly Toops, Ph.D.

+1 (608) 622-334


Minnesota Symposium on Addiction Neuroscience

Your invited to attend the Minnesota Symposium on Addiction Neuroscience, to be held in Minneapolis on September 12th, 2019. The symposium is sponsored by the University of Minnesota's Medical Discovery Team on Addiction.

The day-long conference will bring together basic scientists, clinicians-scientists, and others to discuss the latest, most exciting brain science on addiction. The scientific program will feature plenary sessions, poster presentations, and a keynote speaker, Dr. Yasmin Hurd, Director at the Addiction Institute at Mount Sinai Behavioral Health System. Presentations will emphasize how the neural circuits that control emotions, motivations, and decision-making are altered through addiction and recovery, with an eye towards how neurocircuit science might inform the creation of new, more effective therapies to treat addiction.

The Symposium Planning Committee:

Mark Thomas, PhD (conference chair), Dori Henderson, PhD, Kelvin Lim, MD, Karrie Molitor, Patrick Rothwell, PhD, Sade Spencer, PhD

Click here for more information and registration.