University of Minnesota
University Imaging Center
University Imaging Centers - Where the University sees the future


The University Imaging Centers are Hiring

The University Imaging Centers are Hiring!

We are seeking applicants who are service-oriented team players with excellent interpersonal, organizational and communication skills who enjoy moving science forward using state-of-the-art imaging resources.

The successful candidate will join a team of UIC associates responsible for the daily interactions of a dynamic interdisciplinary core facility at a major research University. This candidate will support and advance imaging projects primarily at our Jackson Hall location. This will include working on widefield, confocal, two photon, in vivo imaging and other efforts by the UIC.

Click here to learn more about current positions available at the UIC!

Demonstrating Research Impact

"Most people think of Experts@Minnesota as a website containing useful information about people and their research." says Jan Fransen, Service Lead for Research Information Management Systems at the University of Minnesota Libraries.

It's true. Experts@Minnesota showcases the expertise of University of Minnesota researchers. It also facilitates collaborations across disciplines and illustrates the impact of the University's world-changing research and creative endeavors.

"But," Fransen adds, "underneath that website is a rich data structure."

Continue reading at the UMN Libraries Continuum.

The UofM will be hosting the Midwest Association of Core Directors (MWACD) Oct 16-18, 2019.

The UofM will be hosting an upcoming conference of the 10TH annual meeting of the Midwest Association of Core Directors (MWACD) to be held October 16 - 18, 2019, TCF Bank Stadium, University of Minnesota, Minneapolis, MN

This meeting will be attended by biomedical research core facility directors, users and administrators from at least 11 states in the Midwest. There will be presentations from leaders of institutional efforts in proteomics, genomics, imaging and administration best practices and decision makers and include speakers from the region on how we can best leverage resources to foster success of current research trends. Cross-core collaborations and technology development will be highlighted with an emphasis on computational approaches for visualization and analysis for researchers of all levels. Scientific presentations, vendors, social events and tours will be part of the activities with keynote presentations from Dr. Michelle Itano from University of North Carolina and Chan Zuckerberg Awardee and our own Dr. Kamil Ugubil from the Center for Magnetic Resonance Research.

I am looking forward to hosting and seeing you all there!


Mark Sanders

Program Director, University Imaging Centers


3i Cleared Tissue LighSheet Microscope (CLTS)


The University Imaging Centers are excited to announce the installation of 3i's Cleared Tissue LightSheet microscope at the UIC Jackson Hall facility.

Cleared Tissue LightSheet (CTLS) is a large field light-sheet microscope designed to image whole organs at high speed. CTLS creates a focused sheet with a narrow waist for better optical sectioning, then uses a spatial light modulator (SLM) to rapidly shift the waist of the sheet along the axis of propagation. A dual excitation setup allows imaging from the right and left sides of the specimen for optimal light-sheet projection throughout. Piezoelectric stages move the specimen in x, y, and z with sub-micron resolution. The result is clear: a 1 cm3 volume can be imaged at up to 1µm x 1µm x 3µm (XYZ) resolution, and a cleared mouse brain can be imaged in as little as 1.5 hours.

Light sheet microscopy is a powerful technique for imaging large specimens by taking full advantage of emerging tissue clearing methods. The chemistry behind these techniques has advanced to where we can easily penetrate 1, 5 even 10mm into a specimen with a focused sheet of light. In combination with a macro zoom microscope using high NA large field of view lenses, Cleared Tissue LightSheet can image large field sizes with high resolution in short periods of timeCTLS acquisition is extremely flexible, from ultrafast capture with a 20μm light sheet to high-resolution capture with a 3μm light-sheet shifted 20 times and the resulting 20 sections of best focus tiled to one best-focus image.